My Dog Is On The Pill

 Dear Supporters, 

 

In this update:

 

I'm happy to report that we've recruited a highly qualified U.S. based Scientific Director. 

 

We have also recruited an additional new chemist, and an additional new veterinarian. 

 

Our Scientific Director has, among other things, also taken the lead in our negotiations with research centers and contract research organizations (CRO's), to speed up the work.

 

I'm also happy to report that each day we are getting closer to success. For example, our studies have produced some of our highest follicle counts to date: a 71% and 68% follicle count, each of course from a single trial cookie (in two of our Pilot Pups) -- which are terrific results. 

 

One of the challenges we face is this: sometimes a single dose works very well, producing follicle counts over 60% ... but sometimes it does not. Currently, it is inconsistent -- and it is crucial that we figure out why, and that we make it consistent.

 

In addition, we are also continuing to investigate more than one possible formula and compound, such as the naturally occurring papaya seed. There are many other substances known to impair fertility, and some are being investigated for possible use as human or animal birth control. We will be posting some of these along with their molecular formulas, soon.  While these have their strong points, there is one that many consider to be "at the head of the pack." 

The compound we have found to be most effective thus far, is the man-made chemical known as VCD: Vinylcyclohexene dioxide, CAS. No. 106-87-6, C8H12O2.  

 

As a multiple-dose formula, it is already approved for use in the U.S. by the EPA, to produce infertility in rodents.  

 

A major difference between this rodent formula, and the formula 600 is working on, is that the rodent formula requires many doses to do the job.

On the other hand, our goal is to produce a formula that will do the job in one dose -- in one Spay and Neuter cookie.   

 

Studies by others have shown that when used as intended, with dogs for example, VCD has proven itself to be safe. Contrast this with: when VCD is in its pure, original state, it is highly concentrated and caustic.  In its concentrated form, it cannot be used because it is too caustic and it must be "watered down."

 

Not only our scientists, but outside scientists as well, believe that this compound is so effective thus far that different versions are expected to help additional mammalian species in need, such as cats, wild horses, deer, coyotes and possibly even ... people.

 

We have also posted photographs of about a dozen of our rescued Pilot Pups.

 

As you know, each Pilot Pup is given a single trial Spay and Neuter Cookie, and then about 30 days later, the pup is spayed or neutered, and the reproductive tissues that are removed as part of the surgery are then histologically examined under a microscope.  

 

These are referred to as histology slides. The histology slides are then examined under a microscope, by specialists: veterinary pathologists in particular.

 

These microscopic examinations allow scientists to determine how effective a particular cookie was, or was not. 

 

We have also posted about a dozen new photographs of histology slides, showing tissues at different stages of their examination. 

 

We are also posting below, for the first time, an example of a histology report.  These are reports by veterinary pathologists, in which they detail their findings as they examine one histology slide at a time.

 

In summary, our scientists are convinced that when completed: the one-dose cookie is destined to have a powerful global impact, benefiting millions of animals ... and thanks to you, we can carry out this life-saving scientific work, which has never been done before.